Allostatic Load: A Review of the Literature

Allostatic Load: A Review of the Literature was funded under the Department of Veterans' Affairs, Applied Research Program and conducted by the Centre for Military and Veterans’ Health.

The report summarises the concepts of homeostasis, allostasis and allostatic load, how chronic stress leads to allostatic load, and examples of the physical and mental conditions which correlate with allostatic load. Allostatic load is an evolving model and only one of several models devised to examine and understand the long term health effects of stress. The model cannot explain all causes of ill-health and disease, however it is emerging as a useful model for investigating how stress experienced during military service may impact negatively on health. There are significant opportunities to improve our understanding of measurement tools and the myriad of challenges related to establishing causality between stress and longer term health outcomes.